What is cyanocobalamine? Discover the benefits and uses of this essential medical compound for health and general welfare.

What is cyanocobalamin? Discover the benefits and uses of this essential medical compound for overall health and well-being.

Cyanocobalamine is a synthetic form of vitamin B12, a vital nutrient that plays a crucial role in various body functions. Also known as vitamin B12 or cobalamine, cyanocobalamine is a hydrosolble vitamin that the human body cannot produce and that must be obtained through diet or supplements. It is an essential cofactor of the enzymes involved in the metabolism of amino acids and fatty acids, as well as in the synthesis of DNA and red blood cells.

Important information:

  1. Cyanocobalamine is usually used to prevent or treat the lack of vitamin B12, which can cause anemia and neurological disorders.
  2. It is available in several forms, including oral tablets, nasal aerosols, sublingual injections and formulations (under the language).
  3. The human body converts cyanocobalamine into methylcobalamine and adenosilcobalamine, active forms of vitamin B12 used by cells.

To better understand the importance of cyanocobalamine, let’s see more closely its role in the maintenance of general health and the benefits it offers.

What is Cyanocobalamin?

One of the main functions of cyanocobalamine is to contribute to the production of red blood cells, which are responsible for transporting oxygen throughout the body. Without an adequate contribution of vitamin B12, the organism cannot produce enough healthy red blood cells, which causes a condition known as megaloblastic anemia. This condition can cause weakness, fatigue, difficulty breathing and other symptoms.

The benefits of cyanocobalamine include:

  1. Favor brain function and cognitive health
  2. Help DNA and RNA formation
  3. Help in carbohydrate, protein and fat metabolism
  4. Increase energy levels and reduce fatigue
  5. Improve mood and general wel l-being

Key Facts about Cyanocobalamin:

– Cyanocobalamine is the most used vitamin B12 shape in supplements and medications.

– It is usually derived from bacterial fermentation processes.

– Cyanocobalamine becomes its active forms, methylcobalamine and adenosilcobalamine, in the body.

– The “cyanocobalamin” compound receives its name from the presence of a cyanide molecule, which is strongly linked and naturally eliminated by the body.

The Definition and Structure of Cyanocobalamin

Cyanocobalamine structure:

  1. Cyanocobalamine belongs to the cobalamin group, which are complex molecules that contain cobalt, carbon, hydrogen, nitrogen, oxygen and sometimes other elements.
  2. Its chemical formula is C63H88con14O14P.
  3. The structure of cyanocobalamine consists of a central cobalt atom surrounded by a corrine ring, a structure similar to hem porphyrine.
  4. To the cobalt atom of cyanocobalamine, a cyano group (CN) is joined, which names the molecule.
  5. Cyanocobalamine also contains a nucleotic loop, which can be of several different types in the different cobalaminas.
Chemical name B12 vitamin
Other names Cyanocobalamine, cobalamin, cobalamide
Chemical formula C63H88CON14O14P
Structural formula Corrine ring with a central cobalt atom, a cyano group attached to cobalt and a nucleotic loop.

Cyanocobalamine is the most stable and common way of vitamin B12 used in medical and pharmaceutical applications, mainly due to its long useful life and its ease of conversion in other active forms of vitamin B12 within the body.

Production and Sources of Cyanocobalamin

Cyanocobalamine sources:

  1. Foods of animal origin: one of the main sources of cyanocobalamine is found in products of animal origin such as meat, birds, fish and dairy products. These foods contain vitamin B12 naturally and are considered excellent sources for people who follow a no n-vegetable or no n-vegan diet.
  2. Enriching foods: To meet the dietary needs of people who follow a vegetarian or vegan lifestyle, many foods are enriched with cyanocobalamine. Among them are fortified cereals for breakfast, dairy alternatives of plant origin and nutritional yeast.
  3. Dietary supplements: cyanocobalamine supplements are available in several forms, such as tablets, capsules and liquid formulas. They can be prescribed by health professionals or acquired without a medical recipe.

It is important to keep in mind that the absorption of cyanocobalamine is a complex process and can vary from one person to another. Factors such as age, digestive health and the presence of certain medications or medical conditions can affect the body’s ability to effectively absorb and use vitamin B12.

Recommended daily cyanocobalamine intake (vitamin B12)
Age group Recommended daily intake
Infants (0-6 months) 0. 4 mcg
Infants (7-12 months) 0. 5 mcg
Children (1-3 years) 0. 9 mcg
Children (4-8 years) 1. 2 mcg
Teenagers (9-13 years) 1. 8 mcg
Adults (from 14 years) 2. 4 mcg

The Role of Cyanocobalamin in the Body

Development and maintenance of nerve cells: Cyanocobalamin is vital for the formation of the protective layer that surrounds nerve cells, known as myelin. This layer helps to insulate and maintain the integrity of nerve fibers, allowing efficient transmission of nerve impulses. Without adequate amounts of cyanocobalamin, nerve function can be compromised, leading to symptoms such as tingling, numbness, and muscle weakness.

“Cyanocobalamin is crucial for the development and maintenance of nerve cells, ensuring efficient transmission of nerve impulses.”

Red blood cell production: Another significant role of cyanocobalamin is its participation in the production of red blood cells. This is essential for transporting oxygen throughout the body. Vitamin B12 is necessary for the maturation of red blood cells in the bone marrow. Without enough cyanocobalamin, red blood cell production can be affected, leading to a disease called megaloblastic anemia. Symptoms of anemia may include fatigue, weakness, difficulty breathing, and pale skin.

DNA synthesis: Cyanocobalamin is also involved in the synthesis of DNA, the genetic material present in all cells in the body. It contributes to the production of new DNA strands during cell division and helps maintain the stability of existing DNA. This is especially important for rapidly dividing cells, such as those in the bone marrow and the lining of the gastrointestinal tract.

  1. Cyanocobalamin is essential for the development and maintenance of nerve cells.
  2. Vitamin B12 is necessary for the production of red blood cells.
  3. Cyanocobalamin is involved in the synthesis and stability of DNA.
Function Effects of deficiency
Development of nerve cells Tingling sensation, numbness, muscle weakness
Red blood cell production Megaloblastic anemia, fatigue, weakness
DNA synthesis Impaired cell division, abnormalities in rapidly dividing cells

Health Benefits of Cyanocobalamin

Vitamin B12 deficiency can cause serious health complications, such as megaloblastic anemia, nerve damage, and cognitive decline. Fortunately, including cyanocobalamin in the diet or through supplements can prevent these problems and provide several health benefits. Here are some of the main health benefits of cyanocobalamin:

  1. Increases energy levels: Cyanocobalamin plays a vital role in converting food into energy by contributing to the metabolism of carbohydrates and fats. This vitamin is essential for maintaining healthy energy levels, reducing fatigue, and increasing overall vitality.
  2. It favors the production of red blood cells: one of the main functions of cyanocobalamine is to contribute to the production of red blood cells. Red blood cells transport oxygen throughout the body, guaranteeing an adequate supply of oxygen to all organs and tissues. An adequate intake of cyanocobalamine helps prevent megaloblastic anemia, which is characterized by weakness, fatigue and difficulty breathing.
  3. It favors brain health: cyanocobalamine is essential to maintain adequate neurological function. It contributes to the formation and maintenance of the protective cover of nerve cells, known as myelin sheath. Proper levels of cyanocobalamine are necessary for optimal cognition, cognition and memory.
Benefits of cyanocobalamin for health:
Rise the levels of energy
Favors the production of red blood cells
Promotes brain health

“Cyanocobalamine plays a crucial role in the maintenance of health and general wel l-being. Its benefits include the increase in energy levels, support for red blood cell production and brain health promotion.”

Possible Side Effects and Risks of Cyanocobalamin

1. Allergic reactions: Some people may be allergic or hypersensitive to cyanocobalamine. Allergic reactions can manifest as skin rashes, itching, swelling or difficulty breathing. If you experience any of these symptoms after taking cyanocobalamine, look for immediate medical attention.

  • Gastrointestinal alterations: Common gastrointestinal side effects of cyanocobalamine can include nausea, vomiting, diarrhea or stomach cramps. These symptoms are usually mild and sel f-limited. If they persist or get worse, it is recommended to consult a healthcare professional.
  • Headache: In some cases, cyanocobalamine supplementation can trigger headaches. If you experience intense or persistent headaches, it is advisable to comment with your health professional. Alternative dose or treatment options can be considered.
  • Interactions with medications: cyanocobalamine can interact with certain medications, such as those used to treat epilepsy, cancer or tuberculosis. These interactions can affect the efficacy or safety of both cyanocobalamine and other medications. It is essential that you inform your doctor of all the medications you take to avoid possible interactions.

A study published in the Journal of the American Medical Association found an association between the lon g-term use of cyanocobalamine supplements in high doses and a greater risk of lung cancer in smokers. However, more research is needed to establish a clear causal relationship.

It is important to follow the dosing instructions recommended by your healthcare professional and discuss any concerns or potential risks with your healthcare professional. Although cyanocobalamin is well tolerated by most people, it is essential to monitor for any unexpected side effects and promptly report them to a healthcare professional for appropriate evaluation and guidance.

Usage and Dosage of Cyanocobalamin as a Supplement

1. Dosage recommendations:

  • The recommended daily dose of cyanocobalamin varies based on age, sex, and specific health conditions.
  • For healthy adults, the typical dose is 2. 4 micrograms per day, which can be obtained through diet or supplements.
  • People with diagnosed cyanocobalamin deficiency may need higher doses. In such cases, it is important to follow the guidance of a healthcare professional.

2. Common forms of cyanocobalamin:

  1. Oral supplements: Cyanocobalamin is usually available in the form of oral tablets or pills. These supplements are easily accessible and usually contain the recommended daily dose of vitamin B12.
  2. Injectable Cyanocobalamin: In some cases, people may need cyanocobalamin injections to treat severe deficiencies or difficulties absorbing the vitamin through the digestive system. These injections are usually administered by healthcare professionals.

Note: It is important to consult with a healthcare professional to determine the appropriate form and dosage of cyanocobalamin supplements based on individual needs and health conditions.

Comparison of administration forms of cyanocobalamin
Dosage form Administration Recommended dose Advantages
Oral supplements Orally 2. 4 micrograms per day Easy to take and widely available
injectable cyanocobalamin Injections Varies depending on the deficiency Direct administration into the bloodstream for faster absorption

Author of the article
Dr.Greenblatt M.
Dr.Greenblatt M.
Medical oncologist at the Robert Larner College of Medicine, MD, at the University of Vermont

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