Know the possible side effects of Inlyta, a medication used in the treatment of certain types of cancer.

Inlyta, also known as Axitinib, is a commonly prescribed medication for the treatment of advanced renal cell carcinoma (a type of kidney cancer) and advanced thyroid cancer. Like any medication, Inlyta can cause various side effects, which can go from slight to serious. It is important that patients know these possible side effects and comment with their doctor.

Inlyta’s most frequent side effects are

• Fatigue
• Diarrhea
• High blood pressure (hypertension)
• Loss of appetite
• Weightloss

In addition to these common side effects, Inlyta can also cause more serious adverse reactions. These may include:

1. Serious bleeding
2. Heart problems, such as myocardial infarction or heart failure
3. Hepatic injury
4. Pulmonary hypertension
5. Thyroid problems

Note: It is essential that patients immediately inform their doctor of any unusual or severe side effect. They should not suspend or adjust their inlyta dose without medical advice.

It is essential that patients receiving INLYTA undergo periodic medical reviews and follo w-up appointments to control their response to treatment and control any possible side effect. Remember that each person can experience side effects differently, so it is important to maintain open communication with health professionals during treatment.

Inlyta Side Effects: What You Should be Aware of

1. Gastrointestinal effects: One of Inlyta’s most frequent side effects are gastrointestinal problems. These may include diarrhea, nausea, vomiting and abdominal pain. It is essential that patients remain well hydrated and notify their healthcare professional any severe or persistent gastrointestinal symptom.

2. High blood pressure: Inlyta can cause an increase in blood pressure levels. This can cause symptoms such as headaches, dizziness, blurred vision and breathing difficulty. It is crucial for patients to regularly control their blood pressure while they take inlyta and inform their doctor if they experience any worrying symptoms.

• 3. Changes in renal function: Inlyta can potentially affect renal function. It is important that the doctor periodically evaluate the patient’s renal function. Any change in urine production, color or presence of blood must be notified immediately.
• 4. 4. Hepatic problems: rarely, Inlyta can cause liver problems. Patients should be attentive to symptoms such as yellowish skin or eyes, dark urine, persistent fatigue and abdominal pain. These signs must immediately communicate to a healthcare professional.
• 5. Wound healing: Inlyta can interfere with the correct healing of wounds after surgical intervention. It is important that patients who are going to undergo surgical intervention inform their surgeon about the use of INLYTA to take adequate precautionary measures and guarantee optimal scar.

Note: This is not an exhaustive list of the side effects associated with Inlyta. Patients should consult their doctor to know in depth the possible risks and side effects.

Understanding the Common Side Effects of Inlyta

Gastrointestinal side effects: INLYTA can cause a series of gastrointestinal side effects, including diarrhea, nausea, vomiting and stomach pain. These side effects are frequent and are usually mild to moderate. However, in some cases, they can become serious and require medical intervention. It is important that patients inform their healthcare providers about any gastrointestinal symptoms to experience so that appropriate measures can be taken to control them.

• Diarrhea: Inlyta can cause an increase in the frequency of stool and soft stools.
• Nausea and vomiting: Some patients may experience sensation of nausea and can vomit while taking inlyta.
• Stomach pain: Inlyta can cause discomfort or abdominal pain.

It is important that patients inform their healthcare providers about any gastrointestinal symptoms to experience so that appropriate measures can be taken to control them.

Hypertension: Inlyta can increase blood pressure levels in some patients. It is important that health professionals regularly control blood pressure during Inlyta treatment. If hypertension is developed, medication or other interventions may be necessary to control blood pressure levels and prevent any associated complication. Patients should inform their doctor of any symptoms such as headaches, dizziness or visual alterations, since they can be signs of hypertension.

Rare But Serious Side Effects of Inlyta

A rare but serious side effect of Inlyta is severe bleeding. Although it is not frequent, it can occur in several places, such as nose, mouth, rectum or urine. If a patient experiences prolonged or excessive bleeding, it is essential that you request immediate medical assistance. Another possible complication associated with the use of Inlyta is the appearance of a gastrointestinal perforation, that is, a breakage or hole in the stomach or intestine. Symptoms of this condition may include intense abdominal pain, fever, chills or vomiting. In such cases, patients should stop taking the medication and immediately notify their doctor.

Important Information:

Secondary effect: severe bleeding

Symptoms: prolonged or excessive hemorrhage by the nose, mouth, rectum or urine.

Measures: seeking immediate medical assistance

SECONDARY EFFECT: Gastrointestinal drilling

Symptoms: Intense abdominal pain, fever, chills or vomiting.

Measures: Stop taking the medication and notify the doctor

It is important to remember that, although these side effects are rare, they should not be ignored. Patients who take inlyta should monitor their wel l-being and quickly inform from any worrying symptom, since an early intervention can significantly improve the results and prevent complications.

Managing and Coping with Side Effects of Inlyta

1. 1. Fatigue: Feeling excessively tired or weak is a frequent side effect of Inlyta. This fatigue can affect the person’s ability to perform routine tasks and can reduce their quality of life. To control fatigue, it is important to give priority to rest and sleep. Planning regular pauses throughout the day, sleeping enough at night and avoiding physically demanding activities can help conserve energy.

• Plan your day: prioritize activities and schedule rest periods between them.
• Sleep enough: try to sleep at least 7-8 hours every night and establish a regular sleep routine.
• Keep active: Practice light or moderate exercise, such as walking or doing yoga, to increase energy levels.
• Follow a balanced diet: adequate nutrition can improve general levels of energy. Include in your meals a variety of fruits, vegetables, lean proteins and whole grains.
• Look for support: Talk to your medical team or join support groups to find advice and get in touch with other people who may be experiencing similar challenges.

Note: If fatigue persists or aggravates, it is important to consult the doctor, since it can indicate other underlying problems that must be treated.

2. Hypertension: Inlyta may cause an increase in blood pressure levels. Controlling and monitoring blood pressure is crucial for general well-being. Regular check-ups with a healthcare professional and following their recommendations are essential for effective management of hypertension caused by Inlyta.

1. Monitor blood pressure: Monitor your blood pressure regularly and keep track of your readings.
2. Follow your doctor’s recommendations: Take prescribed medications as directed and report any changes in blood pressure levels to your doctor.
3. Maintain a healthy lifestyle: Adopting a healthy lifestyle can help control hypertension. This includes eating a balanced diet, exercising regularly, limiting salt intake, and avoiding tobacco and excessive alcohol consumption.
4. Manage stress: Practicing relaxation techniques such as deep breathing, meditation, or engaging in hobbies can help relieve stress and promote overall well-being.
5. Stay hydrated: Drinking an adequate amount of water can help maintain blood pressure levels.

Note: Tell your doctor if you experience severe or persistent hypertension, as dosage adjustments or additional interventions may be necessary to effectively manage this side effect.

How Inlyta Side Effects Differ from Other Cancer Treatments

Patients undergoing cancer treatment often experience a number of side effects as a result of the medication. These side effects can vary depending on the specific drug used and the individual’s unique response to treatment. Inlyta, a targeted therapy commonly used in the treatment of advanced kidney cancer, has its own set of side effects that distinguish it from other cancer treatments.

1. Unique Side Effect Profile:

• Inlyta, also known as axitinib, belongs to a class of drugs called tyrosine kinase inhibitors (TKIs) that work by blocking certain proteins in cancer cells to stop their growth and spread.
• Unlike traditional chemotherapy drugs, which can cause widespread damage to healthy cells in the body, Inlyta primarily acts on specific receptors involved in tumor growth.
• As a result, the side effect profile of Inlyta tends to be different from that of cytotoxic chemotherapy agents and may be more manageable for some patients.

2. Gastrointestinal disorders:

“Gastrointestinal side effects such as diarrhea, nausea and vomiting are commonly reported by patients taking Inlyta.”

• These gastrointestinal disturbances can range from mild to severe and may require supportive medication to relieve symptoms.
• Compared to other treatments against cancer, it is known that Inlyta has a greater incidence of diarrhea, which can be attributed to its specific interactions with gastrointestinal tract receptors.

3. 3. Hypertension:

“Blood pressure elevation is a remarkable side effect associated with inlyta treatment.”

• Patients who take inlyta may experience an increase in blood pressure, which should be closely monitored throughout treatment.
• This side effect is exclusive to the therapies directed as Inlyta and is usually controlled with antihypertensive medications.

Long-term Effects of Inlyta Treatment

One of the lon g-term effects of inlyta treatment is hypertension, also known as high blood pressure. Research has shown that approximately 40-60% of patients receiving INLYTA develop hypertension during treatment. This can happen in the first week after starting treatment and can persist for a long period of time. It is important that health professionals closely control blood pressure levels in patients who receive INLYTA and initiate adequate antihypertensive medication or the modifications of existing regimes to control hypertension.

Important note: hypertension is a frequent side effect of inlyta treatment, which affects a significant proportion of patients. Regular monitoring and control of blood pressure levels are essential to minimize the risk of complications associated with hypertension.

Another possible lon g-term effect of inlyta treatment is hepatotoxicity, which refers to liver toxicity. Studies have shown that alterations of liver function can occur in patients who receive this medication, who often manifest as an increase in liver enzymes. In severe cases, hepatotoxicity can cause liver failure. The control of liver function through periodic blood analysis, including liver enzyme levels, is crucial to identify any possible liver toxicity in patients in inlyta treatment.

• The elevation of liver enzymes may indicate hepatotoxicity in patients receiving inlyta.
• Periodic blood tests to control liver function are essential to detect any potential liver toxicity.

These possible lon g-term effects of inlyta treatment highlight the importance of close surveillance and proactive treatment of patients undergoing this directed therapy. Health professionals must remain attentive to evaluate and treat any adverse effect in order to optimize the results of the patients and guarantee the continuous wel l-being of people who receive inlyta for the treatment of advanced renal cancer.

What to Discuss with Your Doctor Before Starting Inlyta

1. Medical history: Provide your doctor with a detailed medical history, including any past or current medical condition, allergies and surgeries. Certain conditions can affect the security or efficacy of INLYTA, such as liver problems, hypertension, hemorrhagic disorders or thyroid disorders.
2. Medications: reveals all the medications that you are currently taking, including prescription medications, free sales medications, vitamins and supplements. Certain medications can interact with Inlyta, causing potentially serious side effects or reducing its effectiveness. It is especially important to mention anticoagulants, heart medications or medications that affect the immune system.
3. Pregnancy and breastfeeding: If you are pregnant or plan to get pregnant, consult with your doctor the possible risks and benefits of Inlyta. Inlyta is not recommended during pregnancy due to its potential damage to the fetus. Similarly, if you are breastfeeding, it is important that you talk to your doctor about Inlyta’s security for you and your baby.

During the conversation with your doctor, it may be useful to keep a list of questions or doubts about Inlyta. Your doctor may provide personalized information and guidance based on your medical history and your specific needs.

Alternative Treatments for Kidney Cancer and Their Side Effects

1. Herbal Medicine: Many people turn to phytotherapy as an alternative treatment for kidney cancer. It is believed that medicinal herbs such as garlic, ginger and green tea have ant i-cancer properties. However, it is essential to consult with a health professional before incorporating medicinal herbs into the treatment plan, since they can have interactions with prescribed medications.

• Side effects: Although phytotherapy is usually considered safe, it is not exempt from side effects. Some frequent side effects are digestive discomfort, allergic reactions and interactions with medications. For example, ginger can cause acidity or stomach discomfort in some individuals.

2. 2. Acupuncture: This old Chinese practice consists of inserting fine needles into specific points of the body to stimulate energy flow and promote healing. Kidney cancer patients usually resort to acupuncture to control treatment related to pain, nausea and fatigue. However, it is essential to choose a acupuncturer entitled and qualified to minimize the risk of complications.

1. Side effects: In general, acupuncture is considered safe when a qualified professional is performed. However, some people may experience mild side effects, such as bruises, pain or bleeding in the place of insertion of the needle. Rarely, more serious complications, such as infections or organic injuries, may occur if appropriate hygiene and sterilization procedures are not followed.

Note: It is important that patients inform their health team about any alternative treatment they are considering or using. This will help to guarantee coordinated and personalized care while minimizing possible risks or interactions with standard medical treatments.

3. Dietary approaches: Some people opt for diet modifications as an alternative approach to control kidney cancer. These may include the monitoring of specific diets such as ketogenic diet, vegetarian or vegan diet, or the consumption of nutrien t-rich foods. However, it is essential to consult a dietitian or nutritionist entitled to ensure that the chosen diet provides adequate nutrition and does not interfere with the current medical treatments.

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Author of the article

Dr.Greenblatt M.

Medical oncologist at the Robert Larner College of Medicine, MD, at the University of Vermont