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Precautions and Interactions with Other Medications
Precautions:
- Report your doctor about any existing medical condition, including allergies, asthma, liver or renal disease, heart disease, high blood pressure and stomach ulcers.
- Indomethacin can cause dizziness or drowsiness. Be careful when driving or driving machinery until you know how this medicine affects you.
- Avoid consuming alcohol while taking indomethacin, since it can increase the risk of stomach bleeding and can worsen certain side effects.
- Pregnant women should not take indomethacin unless their doctor is specifically prescribed. It can cause damage to the fetus.
Note: It is essential to take indomethacin as prescribed and not exceed the recommended dose. If you experience any serious side effect or an allergic reaction, look for immediate medical attention.
Interactions with other medications:
- NSAIDs (no n-steroidal ant i-inflammatories) such as aspirin, ibuprofen and naproxen can interact with indomethacin and increase the risk of side effects. Therefore, the combination of these medications must be done with caution and under medical supervision.
- Anticoagulant medications (blood diluents) such as warfarin or heparin can increase the risk of hemorrhage when taken concomitantly with indomethacin. It is necessary to regularly control blood coagulation parameters.
- Diuretics can reduce the efficacy of indomethacin and increase the risk of kidney problems. Your doctor may have to adjust the dose or closely monitor your renal function if both medications are required.
| Medication class | Example of medications | Potential interaction |
|---|---|---|
| Antihypertensives | ENALAPRIL, AMLODIPINO | Indomethacin can reduce the effectiveness of antihypertensive medications. |
| Antidepressants | Fluoxetine, sertraline | The combination of indomethacin with certain antidepressants can increase the risk of hemorrhages and stomach ulcers. |
| Antacids | Calcium carbonate, aluminum hydroxide | Taking antacids with indomethacin can decrease its absorption and efficiency. Leave an interval of at least 2 hours between these medications. |
