Discover the benefits of vitamin K supplements for your health and learn how they can contribute to your overall well-being.

Discover the benefits of vitamin K supplements for your health and learn how they can contribute to your general wel l-being.

Vitamin K is a vital nutrient that plays a crucial role in blood clotting and bone health. It contributes to the production of proteins necessary for proper blood clotting and is also involved in bone mineralization. Although the body produces vitamin K naturally, it can also be obtained through dietary sources or supplements. In this article we will discuss the benefits, sources and recommended dosage of vitamin K supplements.

Research shows that vitamin K is essential for blood clotting, as it activates certain proteins that contribute to the formation of blood clots when an injury occurs. It also prevents excessive bleeding by inhibiting the activity of anticoagulant factors. Additionally, vitamin K plays a crucial role in bone health by promoting the incorporation of calcium into bones and preventing bone loss. A vitamin K deficiency can increase the risk of bleeding disorders and weaken bones.

There are two main forms of vitamin K: vitamin K1 (phylloquinone) and vitamin K2 (menaquinone). Vitamin K1 is primarily found in leafy green vegetables, such as kale, spinach, and broccoli, while vitamin K2 is synthesized by bacteria in the gut and can also be found in fermented foods such as natto and cheese. For people who have difficulty incorporating enough vitamin K-rich foods into their diet, vitamin K supplements may be a convenient option.

  1. Vitamin K1 supplements: These supplements contain phylloquinone, the form of vitamin K found in plants. They are usually recommended for people with deficiencies or those who follow a plant-based diet.
  2. Vitamin K2 supplements: These supplements contain menaquinone, derived primarily from bacterial fermentation. They are available in different forms, such as MK-4 and MK-7, each with varying bioavailability.
Foods rich in vitamin K Vitamin K1 content (per 100 g)
Kale 388 mcg
Spinach 482 mcg
Broccoli 226 mcg

Vitamin K Supplementation: A Comprehensive Guide

Vitamin K is a vital nutrient that helps activate the proteins responsible for the coagulation of blood and bone metabolism. It exists in two main ways: vitamin K1 (philoquinone) and vitamin K2 (Menaquinone). While vitamin K1 is mainly found in green leafy vegetables such as spinach and curly, vitamin K2 can be obtained from animal sources such as liver and cheese, as well as fermented foods such as natto. As vitamin K is a liposoluble vitamin, consuming it with food fat improves its absorption.

Did you know what? Vitamin K serves as a cofactor for an enzyme that activates key proteins involved in blood clotting. Vitamin K deficiency can cause prolonged bleeding or even hemorrhages.

Forms of Vitamin K Supplementation:

Vitamin K supplements are presented in different forms, such as pills, capsules and liquid drops. These supplements usually contain vitamin K1 or vitamin K2, or sometimes a combination of both. It is important that you consult with your doctor to determine how and dose are the most appropriate for you.

  • Vitamin K1 supplements: Also known as philoquinone, vitamin K1 is usually used to favor blood clotting. It is usually recommended to people with liver diseases or malabsorption disorders that hinder the absorption of vitamin K in the diet.
  • Vitamin K2 supplements: Menaquinone, or vitamin K2, plays a crucial role in bone metabolism and cardiovascular health. It helps transport calcium to bones and teeth, favoring their resistance and density. There are several vitamin K2 subtypes, such as MK-4 and MK-7, each with their own benefits.

The recommended dose of vitamin K supplements varies depending on age, sex and specific health conditions. In general, adequate vitamin K intake levels for adults are as follows:

Age group Men Women Pregnant Infants
Adults (19+ years) 120 mcg/day 90 mcg/day 90 mcg/day 90 mcg/day
  1. Note: These levels of AI are subject to changes depending on individual needs and should be consulted with a healthcare professional to obtain a personalized orientation.

Understanding the Role of Vitamin K in the Body

Blood coagulation: One of the main functions of vitamin K is to help in blood coagulation. When one is injured and begins to bleed, vitamin K helps activate a protein called prothrombin. Prothrombin then becomes thrombin, which is an enzyme responsible for transforming fibrinogen into fibrin. This fibrin forms a structure similar to a mesh that creates a clot, preventing new bleeding.

Bone health: vitamin K also plays an important role in maintaining healthy bones. It contributes to the formation and maintenance of bone resistance helping to activate specific proteins that regulate calcium metabolism in bone tissue. These proteins, called osteocalcina and protein GLA of the matrix (MGP), are responsible for guaranteeing proper distribution of calcium inside the bones and avoiding calcium deposits in soft tissues and blood vessels.

“Vitamin K exists in two natural forms, vitamin K1 and vitamin K2, both essential for optimal health.”

“Vitamin K is crucial in blood coagulation, helping to activate protrombin and turning it into thrombin, which forms a clot.”

“In addition to blood clotting, vitamin K is necessary to maintain the health of the bones, regulating calcium metabolism and preventing calcium deposits.”

The Role of Vitamin K1 and Vitamin K2

Vitamin K1, or philoquinone, is mainly found in green leafy vegetables such as spinach, curly and brécol. It is the predominant form of vitamin K in the western diet. On the other hand, vitamin K2, or Menaquinona, is mainly synthesized by intestine bacteria or obtained from fermented foods such as cheese and natto, a traditional Japanese food. Vitamin K2 decomposes in turn in different subtypes, such as MK-4 and MK-7, which have slightly different functions in the body.

Vitamin K1 Vitamin K2
The main dietary source is green leafy vegetables The main dietary source is fermented foods or intestinal bacteria
Intervenes in blood coagulation and liver function Intervenes in bone and cardiovascular health
It is considered less bioavailable than vitamin K2 It is considered more biodispononable and has a harsh longer than vitamin K1
  • Vitamin K1 is the main responsible for the coagulation of blood and liver function, while vitamin K2 has a significant impact on bone and cardiovascular health.
  • Vitamin K1 is usually less bioavailable than vitamin K2.
  • Vitamin K2 has a longer semivide, so its effect on the body is more durable than that of vitamin K1.

Types of Vitamin K and Their Sources

Vitamin K1 (phylloquinone)

Philoquinone is the most common form of vitamin K found in plants, especially in green leafy vegetables. It is known for its role in blood coagulation and the maintenance of healthy bones. Espinacas, the curly, the Brécol and the parsley are excellent sources of vitamin K1. Consuming a variety of these vegetables can help guarantee an adequate intake of this important vitamin.

Vitamin K2 (Menaquinone)

Menaquinone is produced by intestine bacteria and is also found in some foods of animal origin. It is believed that this form of vitamin K has a longer semivide in the body than vitamin K1. The best sources of vitamin K2 are fermented foods such as nature, cheese, butter and egg yolks. In addition, some meats, such as liver and chicken, contain small amounts of vitamin K2.

Vitamin K3 (Menadiona)

Unlike K1 and K2 vitamins, vitamin K3 is not found naturally in food. It is a synthetic form of vitamin K that is usually used in supplements. Although its functions are similar to those of other forms of vitamin K, the menadiona is not used so often due to the concern that provokes its possible toxicity in high doses. Therefore, it is important to consult a healthcare professional before taking vitamin K3 supplements.

It should be noted that vitamin K deficiencies are rare, since the organism can recycle and reuse vitamin K. However, certain conditions, such as jugsorption disorders or prolonged use of certain medications, can increase the risk of deficiency. If you suspect that you suffer a lack of vitamin K, it is essential that you go to the doctor to receive an appropriate diagnosis and treatment.

Vitamin K sources by type
Type of vitamin K Sources
Vitamin K1 (phylloquinone) Spinach, curly collar, brécol, parsley
Vitamin K2 (Menaquinone) Natto, cheese, butter, egg yolks, liver, chicken
Vitamin K3 (Menadiona) It is not found naturally in food; It is found in synthetic supplements

In general, incorporating a variety of foods rich in vitamin K into the diet can help guarantee an adequate intake of this important nutrient. However, it is always advisable to consult a healthcare professional before making significant changes in the diet or taking vitamin K supplements.

Benefits of Vitamin K Supplementation

It favors blood coagulation: one of the key functions of vitamin K is its crucial role in the formation of blood clots. It plays a fundamental role in the activation of the proteins responsible for blood clotting, preventing excessive bleeding in the body. Research suggests that vitamin K supplementation can be especially beneficial for people with certain medical conditions or who take anticoagulant medications, since it helps to guarantee adequate coagulation.

Important information:

  1. Vitamin K is essential for blood coagulation and helps in the prevention of excessive hemorrhages.
  2. Vitamin K supplements administration can be beneficial for people with certain medical conditions or who take anticoagulant medications.
  3. It is important to consult with a health professional before starting any supplementation regime with vitamin K.

Improves bone health: Another notable benefit of supplementation with vitamin K is its potential role in promoting bone health. Vitamin K intervenes in the production of proteins that regulate calcium metabolism and bone mineralization. Studies have shown that adequate vitamin K intake can help reduce the risk of osteoporosis and fractures, especially in postmenopausal women. It is important to note that vitamin K acts in synergy with other nutrients, such as vitamin D and calcium, to maintain optimal bone health.

Important information:

  • Vitamin K supplementation can help improve bone health and help reduce the risk of osteoporosis.
  • It is recommended to ensure an adequate intake of other important nutrients, such as vitamin D and calcium, for optimal bone health.
  • People with certain medical conditions or who take medications should consult with a health professional before starting supplementation with vitamin K.

1. Recommended daily amount (CDR):

The recommended daily intake of vitamin K varies depending on factors such as age, sex and the general state of health. According to the Food and Nutrition Council (FNB) of the National Academy of Medicine, the CDR of Vitamin K is the following

  • Infants (0-6 months): 2 micrograms
  • Infants (7-12 months): 2. 5 micrograms
  • Children (1-3 years): 30 micrograms
  • Children (4-8 years): 55 micrograms
  • Men (9-13 years): 60 micrograms
  • Women (9-13 years): 60 micrograms
  • Men (from 14 years): 120 micrograms
  • Women (from 14 years): 90 micrograms
  • Pregnant women: 90 micrograms
  • Women in breastfeeding: 90 micrograms

2. Therapeutic dose:

Although the CDR provides a general guideline for daily vitamin K intake, therapeutic doses may be necessary to treat specific conditions. It is important to consult with a healthcare professional before considering the administration of vitamin K supplements in high doses. The therapeutic doses of vitamin K are often recommended for people with blood coagulation disorders, osteoporosis or certain liver diseases. The recommended therapeutic dose ranges between 100 and 500 micrograms per day, distributed in multiple doses.

Important note: High dose supplementation of vitamin K should only be performed under medical supervision to guarantee your safety and efficacy.

3. Interactions and precautions:

Vitamin K supplements can interact with certain medications and diseases. People who are taking anticoagulant medications such as warfarin or who have a history of blood clotting disorders should consult with their doctor before taking vitamin K supplements. In addition, people with liver or gallbladder disorders may require specialCaution and surveillance when taking vitamin K supplements.

Vitamin K food sources
Food source Vitamin K contained (per 100 g)
Kale 817 micrograms
Spinach 483 micrograms
Broccoli 101 micrograms
Brussels sprouts 177 micrograms
Green peas 24 micrograms
Asparagus 41 micrograms
Prunes 59 micrograms
Kiwi 40 micrograms

Possible Side Effects and Precautions

Possible Side Effects

  • 1. Allergic reactions: Some individuals may experience allergic reactions to vitamin K supplements. Symptoms may include cutaneous eruption, itching, swelling, dizziness or breathing difficulty. If you experience any of these symptoms, interrupt your use and look for medical attention immediately.
  • 2. 2. Digestive problems: High doses of vitamin K supplements can cause gastrointestinal discomfort, such as nausea, stomach cracks or diarrhea. If you experience any of these symptoms, it is recommended to reduce the dose or interrupt its use.
  • 3. Interactions with medications: vitamin K supplements can interact with certain medications, including anticoagulants such as warfarin. This can affect the ability of blood to coagulate correctly. If you are taking any medication, especially anticoagulants, it is crucial to report your health professional before taking vitamin K supplements.

Precautions

  1. 1. Dose: It is important to follow the dosing guidelines recommended by the manufacturer or the health professional. Taking excessive amounts of vitamin K supplements can have adverse health effects.
  2. 2. 2. Medical conditions: People with certain medical conditions, such as liver or renal problems, may have to take care when taking vitamin K supplements. It is best to consult with a health professional to determine if the supplementation is suitable forYour specific condition.
  3. 3. Pregnancy and breastfeeding: pregnant or breastfeeding women should consult their health professional before taking vitamin K supplements to make sure it is safe for both the mother and the baby.

Remember that it is always essential to consult with a health professional before starting to take any supplement, including vitamin K. They can provide personalized advice based on their specific medical history, their current medications and their dietary needs.

Interactions of Vitamin K with Other Medications

One of the medications that can interact with vitamin K is warfarin, a common anticoagulant used to prevent blood clots. Vitamin K and warfarin have a complex relationship, since vitamin K intervenes in the formation of blood clots while warfarin inhibits this process. Therefore, when taking warfarin, it is important to maintain a constant intake of vitamin K to guarantee the effectiveness of the medication. An abrupt change in vitamin K intake can cause fluctuations in the efficacy of warfarin and increase the risk of hemorrhages or clots.

Important note: If you are taking warfarin, it is essential that you inform your doctor of any change in vitamin K intake, including diet changes or the addition of a vitamin K supplement, to ensure optimal anticoagulant effects.

Another medicine that can interact with vitamin K are certain antibiotics, such as tetracycline and headache. These antibiotics can interfere with the intestinal absorption of vitamin K, which can cause a lack of it. This can affect blood coagulation and increase the risk of hemorrhages. People who take these antibiotics may need to control their vitamin K levels and consider supplements administration under the supervision of a healthcare professional.

  1. Warfarin: Maintain a constant vitamin K intake to avoid fluctuations in the efficacy of warfarin.
  2. Certain antibiotics: interfere with the absorption of vitamin K, being able to cause a deficiency.
Medicines Interaction with vitamin K
Warfarin Affects anticoagulant effects; Maintain a constant intake of vitamin K.
Certain antibiotics Interfere with the absorption of vitamin K; Control levels and consider supplements administration.

Choosing the Right Vitamin K Supplement for You

Type of vitamin K: There are two main forms of vitamin K: vitamin K1 (philoquinone) and vitamin K2 (Menaquinone). Vitamin K1 is found in green leafy vegetables and is essential for blood clotting. On the other hand, vitamin K2 is synthesized by intestine bacteria and is related to bone and cardiovascular health. It is important to choose a supplement that provides the specific type of vitamin K that fits its health objectives.

  • Vitamin K1: Favor the coagulation of blood and liver health.
  • Vitamin K2: It favors bone health and cardiovascular function.

Dosage: The proper dose of vitamin K supplement depends mainly on your individual needs and your health status. Consult a healthcare professional or dietitian entitled to determine the appropriate dose for you. Although vitamin K’s shortcomings are rare, excessive intake can also have adverse effects, especially in people who take anticoagulant medications. It is essential to find a balance and make sure to be taking the correct dose.

Supplement shape: vitamin K supplements are available in several forms, such as capsules, tablets and liquids. Take into account your personal preferences and the ease of administration when choosing a supplement. In addition, check if the chosen form contains additional or possible allergens.

Tables Showing Various Vitamin K Supplements:

Brand Type of vitamin K Dose Shape
Brand a Vitamin K1 100 mcg Capsules
Brand b Vitamin K2 50 mcg Tablets
Brand c Vitamin K1 and K2 mixture 200 mcg Liquid

Key Takeaways:

  1. Pose in mind the specific type of vitamin K you need for your health objectives.
  2. See with a healthcare professional to determine the appropriate dose.
  3. Evaluate the shape of the supplement according to your personal preferences and the ease of administration.

Author of the article
Dr.Greenblatt M.
Dr.Greenblatt M.
Medical oncologist at the Robert Larner College of Medicine, MD, at the University of Vermont

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