Discover the benefits and uses of Polymixin HC neomycin, a powerful medical treatment for various conditions.

Discover the benefits and uses of Neomycin Polymyxin HC, a powerful medical treatment for various conditions.

When it comes to fighting bacterial infections, Neomycin Polymyxin HC has proven to be a very effective treatment option. This medicine, a combination of neomycin, polymixin B and hydrocortisone, offers a powerful solution for a wide range of conditions caused by susceptible bacteria. These are already cutaneous, ocular or otitis infections, Polymixin HC neomycin has been widely prescribed by health professionals due to their powerful antibacterial and ant i-inflammatory properties.

Important information: Polymixin HC neomycin is not only effective against most bacteria strains, but also provides relief of symptoms associated with bacterial infections. However, it is important to keep in mind that this medicine is only available with a medical recipe and should never be used without adequate medical supervision. In addition, people with known hypersensitivity to any of the active ingredients of this medication should avoid its use.

Ulcers, conjunctivitis and external otitis are just some examples of conditions that can be treated effectively with polymixin HC neomycin. This medicine acts inhibiting the growth and reproduction of bacteria, eliminating infection. In addition, the addition of hydrocortisone, a corticosteroid, helps reduce inflammation and redness of affected areas, providing relief to patients.

  1. Table 1: Common Uses of Polymixin HC Neomycin
Condition Application
Cutaneous infections (for example, impetigo) Topical cream, ointment
Eye infections (eg, conjunctivitis) Ophthalmic solution, ointment
Ear infections (eg, external otitis) Otic solution, suspension

Overview of Neomycin Polymyxin HC: Uses, Benefits, and Side Effects


  • Treatment of bacterial skin infections: Polymixin HC neomycin is usually prescribed for the treatment of skin infections caused by bacteria. It acts inhibiting the growth and spread of bacteria, helping to eliminate infection and reduce inflammation.
  • Prevention of skin infections: In some cases, this medicine can be used to prevent skin infections before and after surgical procedures. It acts as a protective barrier against possible bacterial contamination.
  • Dermatitis and eczema control: the hydrocortisone component of Polymixin HC Neomycin provides itching of itching, redness and inflammation associated with dermatitis and eczema.


The combination of neomycin and polymyxin B sulfate in Neomycin Polimyxin HC provides broad-spectrum coverage against a number of bacteria. This allows the medication to effectively target and kill the bacteria causing the infection.

The inclusion of hydrocortisone in the formulation offers additional benefits by reducing inflammation, itching and discomfort associated with certain skin conditions.

Side effects:

Although Neomycin Polymyxin HC can be very beneficial, it can also cause certain side effects. The most common side effects include mild skin irritation, redness, and itching at the application site. Rarely, some people may experience an allergic reaction, characterized by severe itching, swelling, or a rash. If any serious or persistent side effects occur, it is important to seek medical attention immediately.

Common uses Potential benefits Side effects
Treatment of bacterial skin infections Broad spectrum coverage against bacteria Mild skin irritation
Prevention of skin infections Reduces inflammation Redness at the application site
Control of dermatitis and eczema Relieves itching and discomfort Allergic reactions (rare)

What is Neomycin Polymyxin HC and How Does It Work?

Neomycin and polymyxin are antibiotics that belong to the group of drugs known as aminoglycosides and polymyxins, respectively. These antibiotics work by altering the bacteria’s ability to grow and reproduce, ultimately leading to their death. Neomycin acts specifically against gram-negative bacteria, while polymyxin is effective against a wide range of bacteria, including some gram-negative species resistant to other antibiotics.

Neomycin Polimyxin HC is a combination of the antibiotics neomycin and polymyxin, along with hydrocortisone, an anti-inflammatory agent. It is primarily used to treat bacterial infections of the eyes and ears, and is available in the form of ear drops, ointment, and solution for external use.

How does Neomycin Polymyxin HC work?

When Neomycin Polimyxin HC is applied to the affected area, such as the eye or ear, it acts by inhibiting the growth and multiplication of bacteria. Neomycin works by interfering with the production of essential proteins necessary for bacterial survival, ultimately leading to the destruction of the bacteria. Polymyxin, for its part, acts by altering the bacterial cell membrane, causing the leakage of cellular contents and the death of the bacteria.

In addition to its antibiotic action, Neomycin Polimyxin HC also contains hydrocortisone, which helps reduce inflammation and relieve symptoms such as redness, swelling and itching. Hydrocortisone belongs to the class of medications known as corticosteroids, which have powerful anti-inflammatory properties. By suppressing the immune response and reducing inflammation, hydrocortisone helps relieve discomfort and promotes the healing process.

  1. Neomycin Polymyxin HC inhibits the growth and multiplication of bacteria.
  2. Neomycin interferes with protein synthesis in bacteria.
  3. Polymyxin disrupts the bacterial cell membrane.
  4. Hydrocortisone reduces inflammation and relieves symptoms.

The combination of neomycin, polymyxin and hydrocortisone in Neomycin Polimyxin HC makes it a versatile and effective medication for the treatment of bacterial infections, as it provides both antimicrobial and anti-inflammatory actions.

Medical Uses of Neomycin Polymyxin HC

One of the main medical uses of Neomycin Polymyxin HC is the treatment of external ear infections, also known as otitis externa or swimmer’s ear. This condition occurs when the ear canal becomes infected, causing symptoms such as pain, itching, and discharge. Neomycin Polymyxin HC is a commonly recommended treatment option for otitis externa as it effectively addresses the underlying bacterial cause of the infection.

  • Ear infections: Neomycin Polimyxin HC is commonly prescribed to treat external ear infections, relieving symptoms such as pain, itching and discharge.
  • Eye infections: This medication is also used to combat eye infections caused by susceptible bacteria, such as conjunctivitis or conjunctivitis.
  • Skin infections: Neomycin polymyxin HC is often used in the treatment of skin infections caused by bacteria, such as impetigo and infected wounds.

The combination of neomycin and polymyxin in Neomycin Polymyxin HC acts synergistically to inhibit bacterial growth and ultimately eliminate the infection.

Neomycin Polimyxin HC is available in various forms, such as ointments, creams and drops, making it versatile for different applications. However, it is crucial to note that this medication should only be used as prescribed by a healthcare professional, as inappropriate or excessive use can lead to antibiotic resistance or other adverse effects. Therefore, always follow your healthcare professional’s instructions and complete the entire treatment for best results.

Medical uses Administration Common side effects
ear infections Ear drops or ointments applied to the affected ear Temporary hearing loss, itching, irritation
Eye infections Eye drops or ointments applied to the affected eye Eye irritation, redness, blurred vision
skin infections Ointments or creams applied topically to affected skin Skin irritation, itching, rash

Possible Side Effects and Precautions

Side effects

There are several potential side effects associated with Neomycin Polimyxin HC:

  1. Local irritation: Some people may experience irritation, redness or itching at the application site. If these symptoms persist or worsen, it is advisable to seek medical attention.
  2. Allergic reactions: Although rare, some people may develop an allergic reaction to the medication. This may manifest as hives, rash, swelling, or difficulty breathing. If any of these symptoms occur, immediate medical assistance is required.
  3. Hearing loss: Neomycin, one of the active ingredients in this medication, can cause hearing loss. This is more likely to occur in individuals with pre-existing hearing problems or those on long-term treatment. It is recommended to report any changes in hearing to a healthcare professional.


It is important to take certain precautions during the use of Neomycin Polimyxin HC to ensure safe and effective use:

  • Avoid contact with eyes: This medication should not come into contact with the eyes as it may cause irritation or damage to the delicate eye structures. In case of accidental contact, it is recommended to rinse thoroughly with clean water.
  • Ongoing medical conditions: People with certain medical conditions, such as kidney disease or myasthenia gravis, may require special monitoring or dosage adjustments. It is crucial to inform the healthcare professional prescribing the medication of any pre-existing conditions.
  • Pregnancy and breast-feeding: The safety of Neomycin Polimyxin HC during pregnancy and breast-feeding has not been established. It is essential to consult a healthcare professional before using this medication if you are pregnant or breast-feeding.

It is crucial to follow the prescribed dosage and not exceed the recommended duration of treatment without medical advice.

By knowing the possible side effects and taking the necessary precautions, people can optimize the use of Neomycin Polimyxin HC and minimize the risks associated with its use.

Drug Interactions with Neomycin Polymyxin HC

An important pharmacological interaction to consider is diuretics. Diuretics are usually prescribed to patients with diseases such as hypertension or edema. When combined with Polymixin HC neomycin, diuretics can increase the risk of renal damage. It is recommended to closely monitor renal function and adjust the dose of both medications if necessary.

Another important pharmacological interaction affects anticoagulant medications, such as warfarin. Polymixin HC neomycin can enhance the anticoagulant effect of warfarin, increasing the risk of bleeding. Patients who use both medications should have closely controlled their International Normalized Reason (INR), and the necessary dose adjustments should be performed. It is crucial to communicate this interaction to patients to prevent potentially mortal complications.

Important Drug Interactions with Neomycin Polymyxin HC:

  1. Diuretics: Polymixin HC neomycin can increase the risk of renal damage when combined with diuretics. Control renal function and adjust the dose accordingly.
  2. Anticoagulant medications (for example, warfarin): Polymixin HC neomycin can enhance the anticoagulant effect, increasing the risk of bleeding. Regularly control the INR levels and make the necessary dose adjustments.
  3. Oral contraceptives: Polymixin HC Neomycin can reduce the effectiveness of oral contraceptives. Discuss alternative contraceptive methods with patients who use both medications.


By using Polymixin HC neomycin, it is essential to take into account the possible medication interactions to guarantee a safe and effective treatment. Certain medications, such as diuretics and anticoagulants, can interact with polymixin HC neomycin, increasing the risk of renal damage and hemorrhage, respectively. It is crucial to closely monitor patients who use these medications and make the necessary settings to avoid complications.

Tips for Safe and Effective Use of Neomycin Polymyxin HC

  1. Follow the prescribed dosage: Always follow the dosing instructions provided by your health professional or those indicated in the container. Polymixin HC neomycin is normally administered in the form of ophthalmic drops, and the exact frequency and duration of its use will depend on the specific condition that is being treated.
  2. Wash your hands: before applying the columus, it is essential to wash your hands well with soap and water. This helps minimize the risk of introducing additional bacteria or pollutants in the eye.
  3. Administer with caution: When instillance the eye drops, slightly tilt your head back and gently pull down the lower eyelid to create a small bag. Avoid touching the tip of the dropper to avoid pollution. Next, close the eye gently for a few seconds to guarantee the correct distribution of the medication.

Tip: If you are not sure what is the right technique to instill the columus, consult your doctor or pharmacist to make a demonstration.

In addition to these steps, it is important to know the possible side effects or precautions associated with polymixin HC neomycin. This medicine can cause temporary blurred vision or stinging sensation after application. If these symptoms persist or get worse, look for medical attention.

Important considerations:
Pregnancy and breastfeeding: Report to your healthcare professional if you are pregnant, you plan to become pregnant or in a lactation period, since Polymixin HC neomycin may not be appropriate for all people in these situations.
ALLERGIAS: If you have known allergy to any of the Polymixin HC Neomycin components or similar medications, report to your medical care provider to avoid possible adverse reactions.
Other medications: Report to your health professional about any existing medication, supplements or eye drops that you are currently using to prevent any potential interaction with Polymyxin HC Neomycin.

Remember that polymixin HC neomycin is specifically prescribed for you based on your health status, so it is essential that you use it according to your health professional. If you have any questions or questions about your use, do not hesitate to consult a health professional to guide you.

Alternative Treatments for Neomycin Polymyxin HC

An alternative treatment for polymixin HC neomycin is the use of a different antibiotic. Although polymixin HC neomycin is effective against a wide range of bacteria, there are other antibiotics that can be equal or more effective depending on specific infection. For example, erythromycin and gentamycin are two alternatives to take into account. These antibiotics have different mechanisms of action and can be directed against bacteria against which Polymixin HC neomycin may not be so effective.

Important note: It is essential to consult a healthcare professional before making any change in medication or treatment plans. They can guide and determine the most appropriate alternative treatment depending on individual circumstances.

Another alternative treatment is to use natural remedies or complementary therapies to treat eye infections or inflammations. These options can alleviate and promote the healing process without the possible side effects associated with drugs. One option is to use warm compresses or saline eye rinses to reduce inflammation and cleanse the eye. Additionally, certain medicinal herbs such as chamomile or eyebright extracts have been traditionally used for their anti-inflammatory and antimicrobial properties.

  • Hot Compresses: Apply a hot compress to the affected eye for 10-15 minutes, several times a day.
  • Saline eye rinses: Mix 1 teaspoon salt with 1 cup distilled water, boil, and let cool before use. Gently rinse the eye with the solution.
Herbal remedies Properties
Chamomile Anti-inflammatory
eyebright Antimicrobial

It is important to note that alternative treatments should not be used as substitutes for prescribed medications without medical supervision. They should be considered in conjunction with professional advice and as a complementary part of a comprehensive treatment plan.

Author of the article
Dr.Greenblatt M.
Dr.Greenblatt M.
Medical oncologist at the Robert Larner College of Medicine, MD, at the University of Vermont

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